Pirlindole-d4 HCl
Pirlindole-d4 is intended for use as an internal standard for the quantification of pirlindole by GC- or LC-MS. Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor. It is selective for MAO-A over MAO-B. In rats, it reverses the depressive-like effects induced by chronic mild stress (CMS), increases proliferation of hippocampal neural progenitor cells, and reverses dendritic atrophy in granule neurons. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3), inhibiting the genome replication phase of CV-B3 infection with an EC50 value of 7.7 µM independent of MAO-A activity.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1103 |
| CAS # | 1801617-88-8 |
| Pricing | Customizable size, Inquiry |
| Synonym | Pirlindole-d4 HCl; Pirlindole d4 HCl; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C15H15D4ClN2 |
| Exact Mass | 266.1488 |
| Molecular Weight | 266.8054 |
| Elemental Analysis | C, 67.53; H, 8.69; Cl, 13.29; N, 10.50 |
| IUPAC/Chemical Name | 8-methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole-1,1,2,2-d4 hydrochloride |
| InChi Key | LIFOOCLGAAEVIF-UVSTZUAESA-N |
| InChi Code | InChI=1S/C15H18N2.ClH/c1-10-5-6-14-12(9-10)11-3-2-4-13-15(11)17(14)8-7-16-13;/h5-6,9,13,16H,2-4,7-8H2,1H3;1H/i7D2,8D2; |
| SMILES Code | CC1=CC=C2N3C([2H])(C([2H])(NC4CCCC(C2=C1)=C34)[2H])[2H].Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |