Human Anti-SELL Recombinant Antibody (clone HuDREG-55); scFv Fragment
The participation of L-selectin in leukocyte recruitment during inflammation has suggested the use of L-selectin inhibitors as potential anti-inflammatory therapeutics. Blocking monoclonal antibodies could serve as such therapeutic agents. HuDREG-55 block L-selectin-dependent adhesion of human lymphocytes to high endothelial venules in frozen sections of lymph nodes. In addition, HuDREG-55 are inhibitory in a novel L-selectin-dependent adhesion assay.
| Supplier | Creative Biolabs |
|---|---|
| Product # | FAMAB-0210-YC-S(P) |
| Pricing | Inquiry |
| Host | Human |
| Target | SELL |
| Species Reactivity | Human, Cynomolgus, Monkey, Chimpanzee, Baboon |
| Type | Humanized scFv |
| Applications | FC, FuncS |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |