SHR0302
Supplier | MedChemExpress |
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Product # | HY-112724-10 mg |
CAS # | 1445987-21-2 |
Pricing | 10 mg, USD $1300.0 |
Biological Activity | SHR0302 is a potent and orally active all members of the JAK family inhibitor, particularly JAK1. The selectivity of SHR0302 for JAK1 is >10-fold for JAK2, 77-fold for JAK3, 420-fold for Tyk2. SHR0302 inhibits JAK1-STAT3 phosphorylation and induces the apoptosis of hepatic stellate cells. SHR0302 has anti-proliferative and anti-inflammatory effects[1][2]. |
Purity | 99.58% |
MWt | 414.48 |
Formula | C₁₈H₂₂N₈O₂S |