4-Hydroxyisoleucine
4-Hydroxyisoleucine, which comes from the seeds of Trigonella foenum-graecum L, could inhibit palmitate-induced, ROS-associated inflammation and restored insulin sensitivity through regulating IRS-1 function. It acts to improve insulin resistance by promoting mitochondrial biogenesis in high fructose diet fed STZ induced diabetic rats. Besides, 4-Hydroxyisoleucine could remarkably improve high glucose-induced IR in 3T3-L1 adipocytes. Meanwhile, 4-HIL could inhibit the secretion of TNF-alpha.
| Supplier | BOC Sciences |
|---|---|
| Product # | B0005-347850 |
| Pricing | Inquire |
| Cas | 781658-23-9 |
| Molecular Weight | 147.17 |
| Molecular Formula | C6H13NO3 |
| Canonical SMILES | CC(C(C)O)C(C(=O)O)N |