TAK-960 dihydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15160B-10 mg |
| Pricing | 10 mg, USD $216.0 |
| Biological Activity | TAK-960 dihydrochloride is an orally available, selective inhibitor of polo-like kinase 1 (PLK1), with an IC50 of 0.8 nM. TAK-960 dihydrochloride also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16.9 and 50.2 nM, respectively. TAK-960 dihydrochloride inhibits proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts[1]. |
| Purity | 99.81% |
| MWt | 634.52 |
| Formula | C₂₇H₃₆Cl₂F₃N₇O₃ |