FGTI-2734
Supplier | MedChemExpress |
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Product # | HY-128350-50 mg |
CAS # | 1247018-19-4 |
Pricing | 50 mg, USD $2000.0 |
Biological Activity | FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 250 nM and 520 nM for FT and GGT-1, respectively. FGTI-2734 can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors[1]. |
Purity | 99.48% |
MWt | 510.63 |
Formula | C₂₆H₃₁FN₆O₂S |