FGTI-2734

Supplier MedChemExpress
Product # HY-128350-50 mg
CAS # 1247018-19-4
Pricing 50 mg, USD $2000.0
Biological Activity FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 250 nM and 520 nM for FT and GGT-1, respectively. FGTI-2734 can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors[1].
Purity 99.48%
MWt 510.63
Formula C₂₆H₃₁FN₆O₂S
Feedback