FGTI-2734 mesylate

Supplier MedChemExpress
Product # HY-128350A-10 mg
Pricing 10 mg, USD $650.0
Biological Activity FGTI-2734 mesylate is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT) inhibitor with IC50s of 250 nM and 520 nM for FT and GGT, respectively. FGTI-2734 mesylate can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors[1].
Purity 98.73%
MWt 606.73
Formula C₂₇H₃₅FN₆O₅S₂
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