Tanespimycin (17-AAG)
Tanespimycin (17-AAG, CP127374, NSC-330507, KOS 953) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Tanespimycin (17-AAG) induces apoptosis, necrosis, autophagy and mitophagy. Phase 3.
Supplier | Selleck Chemicals |
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Product # | S1141 |
Sku # | S1141-10mM/1mL |
Pricing | 10mM/1mL, $117.00 |