Anti-mouse CD40L (CD154)-InVivo
The MR-1 monoclonal antibody reacts with mouse CD154 also known as CD40 ligand. The MR-1 monoclonal antibody has been reported to inhibit in vitro activation of B lymphocytes by blocking the binding of CD154 with CD40 on T helper cells as well as inhibit the formation of germinal centers and disrupt antigen-specific T cell responses. Additionally, the MR-1 antibody blocks interactions of T cells and antigen-presenting cells in vitro and blocks the development of experimental autoimmune disease in vivo.
Supplier | Selleck Chemicals |
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Product # | A2112 |
Sku # | A2112-5mg*5 |
Pricing | 5mg*5, $919.00 |