RG-12525
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-101676-10 mg |
| CAS # | 120128-20-3 |
| Pricing | 10 mg, USD $580.0 |
| Synonyms | NID 525 |
| MWt | 423.47 |
| Formula | C₂₅H₂₁N₅O₂ |
| Biological Activity | RG-12525 is a a specific, competitive and orally effective antagonist of the peptidoleukotrienes, LTC4, LTD4 and LTE4, inhibiting LTC4-, LTD4- and LTE4-inducd guinea pig parenchymal strips contractions, with IC50s of 2.6 nM, 2.5 nM and 7 nM, respectively; RG-12525 is also a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist with IC50 of appr 60 nM and a potent inhibitor of CYP3A4, with a Ki value of 0.5 µM. |
| Purity | 98.39% |