(R)-Gyramide A hydrochloride

Supplier MedChemExpress
Product # HY-109785A
CAS # 1793050-70-0
Pricing inquire
Biological Activity (R)-Gyramide A hydrochloride is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 µM. (R)-Gyramide A hydrochloride demonstrates antibacterial activity against E. coli, P. aeruginosa, and S. enterica (MICs of 10-80 µM). (R)-Gyramide A hydrochloride does not affect the closely related enzyme topoisomerase IV.
MWt 442.98
Formula C₂₁H₂₈ClFN₂O₃S
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