Anti-Human FGFR1 Therapeutic Antibody scFv Fragment (FR1-H7)
Antibody FR1-H7 binds FGFR-1(IIIb) and -1(IIIc) with strong affinities, but does not recognize any of the other FGFRs. Results from kinetic analysis indicated the antibody binds to FGFR-1b and -1c equally well. The KDs of the interactions were determined to be approximately 50 μM for both receptors. This product can be potentially used for antagonizing EGFR-1 or EGFR-4 as a treatment for obesity, diabetes, or a condition related thereto, and methods of reducing food intake.
| Supplier | Creative Biolabs |
|---|---|
| Product # | TAB-052WM-S(P) |
| Pricing | Inquiry |
| Host | Human |
| Target | FGFR1 (Fibroblast growth factor receptor 1) |
| Species Reactivity | Human |
| Type | Human Antibody |
| Applications | Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Neutralization; Blocking |