IMP-1088

Supplier MedChemExpress
Product # HY-112258-1 mg (22.05 mM * 100 μL in Methyl acetate)
CAS # 2059148-82-0
Pricing 1 mg (22.05 mM * 100 μL in Methyl acetate), USD $475.0
Biological Activity IMP-1088 is a potent human N-myristoyltransferases NMT1 and NMT2 dual inhibitor with IC50s of <1 nM for HsNMT1 and HsNMT2. IMP-1088 has a Kd of <210 pM for HsNMT1. IMP-1088 efficiently blocks rhinovirus replication by blocking rhinovirus virus-encoded protein (VP0) N-myristoylation. IMP-1088 protects host cells from the cytotoxic effects of viral infection[1].
Purity ≥98.0%
MWt 453.53
Formula C₂₅H₂₉F₂N₅O
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