Aspartocin D

Aspartocin D is a minor analogue of the amphomycin complex, a family of lipopeptide antibiotic produced by Streptomyces canus. Aspartocin D has the activity against Gram-positive bacteria with MIC of 0.125 μg/ml for B. subtilis and is presumed to act by inhibiting bacterial cell wall peptidoglycan synthesis, however its bioprofile and potential utility has not been extensively investigated. The antibacterial activity is calcium-dependent, with MICs ranging from 0.06-4 and 0.25-8 μg/ml for B. subtilis and S. aureus, respectively, in the presence of higher (2.5 mM) to lower (0.125 mM) calcium concentrations.

• Supplier: BOC Sciences
• Product #: BBF-04212
• Cas: 1562369-96-3
• Molecular Weight: 1262.37
• Molecular Formula: C56H87N13O20
• Canonical SMILES: CC1C(C(=O)N2CCCCC2C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N3CCCC3C(=O)N1)C(C)C)C(C)N)CC(=O)O)CC(=O)O)C(C)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)CC=CCCCCC(C)C