Diflapolin
Supplier | MedChemExpress |
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Product # | HY-128171-100 mg |
CAS # | 724453-98-9 |
Pricing | 100 mg, USD $800.0 |
Biological Activity | Diflapolin is a highly active dual 5-lipoxygenase-activating protein (FLAP)/soluble epoxide hydrolase (sEH) inhibitor with marked anti-inflammatory efficacy and high target selectivity. Diflapolin inhibits 5-LOX product formation in intact human monocytes and neutrophils with IC50s of 30 and 170 nM, respectively, and suppressed the activity of isolated sEH (IC50=20 nM)[1]. |
Purity | 99.42% |
MWt | 458.36 |
Formula | C₂₂H₁₇Cl₂N₃O₂S |