BL-1249
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-108596-10 mg |
| CAS # | 18200-13-0 |
| Pricing | 10 mg, USD $400.0 |
| Biological Activity | BL-1249 is a nonsteroidal anti-inflammatory drug (NSAID) and a potassium channel activator. BL-1249 potently activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) with EC50 values of 5.5 μM and 8.0 μM, respectively. BL-1249 extracellular application activates all TREK subfamily members but has no effect on other K2P subfamilies. BL-1249 exhibits more selective for the bladder (EC50 of 1.26 μM) than vascular tissue (EC50 of 21.0 μM)[1][2]. |
| Purity | ≥99.0% |
| MWt | 291.35 |
| Formula | C₁₇H₁₇N₅ |