S14-95
S14-95 is an inhibitor of the JAK/STAT pathway isolated from Penicillium sp. 14-95. It inhibits the IFN-gamma mediated expression of the reporter gene with IC50 values of 2.5 to approximately 5 mg/ml. It inhibits the expression of the proinflammatory enzymes COX-2 and NOS II at 5 microg/ml (10.8 mM) in LPS/IFN-gamma stimulated J774 mouse macrophages.
| Supplier | BOC Sciences |
|---|---|
| Product # | BBF-03392 |
| Pricing | Inquire |
| Molecular Weight | 450.57 |
| Molecular Formula | C28H34O5 |