GDC-0623
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15610-10 mg |
| CAS # | 1168091-68-6 |
| Pricing | 10 mg, USD $250.0 |
| Biological Activity | GDC-0623 (RG 7421) is a potent, ATP-uncompetitive inhibitor of MEK1 (Ki=0.13 nM, +ATP), and displays 6-fold weaker potency against HCT116 (KRAS (G13D), EC50=42 nM) versus A375 (BRAFV600E, EC50=7 nM). |
| Synonyms | RG 7421; MEK inhibitor 1 |
| MWt | 456.21 |
| Formula | C₁₆H₁₄FIN₄O₃ |