PQ401
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13686-10 mM * 1 mL |
| CAS # | 196868-63-0 |
| Pricing | 10 mM * 1 mL, USD $127.0 |
| Biological Activity | PQ401 is a potent inhibitor of IGF-IR signaling. PQ401 inhibits IGF-I-stimulated IGF-IR autophosphorylation with an IC50 of 12.0 μM in a series of studies in MCF-7 cells. PQ401 is effective at inhibiting IGF-I-stimulated growth of MCF-7 cells (IC50, 6 μM). PQ401 is a potential agent for breast and other IGF-I-sensitive cancers. PQ401 induces caspase-mediated apoptosis[1]. |
| Purity | 99.88% |
| MWt | 341.79 |
| Formula | C₁₈H₁₆ClN₃O₂ |