DCLK1-IN-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-135985-5 mg |
| CAS # | 2222635-15-4 |
| Pricing | 5 mg, USD $450.0 |
| Biological Activity | DCLK1-IN-1 is a selective, oral bioavailability in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1 kinase) domain. DCLK1-IN-1 inhibits DCLK1 and DCLK2 kinases (IC50: DCLK1=9.5/57.2 nM and DCLK2=31/103 nM in binding and kinase assay, respectively). DCLK1-IN-1 shows low toxicity, and can investigate DCLK1 biology and establish its role in cancer, like DCLK1+ pancreatic ductal adenocarcinoma (PDAC)[1]. |
| Purity | 99.48% |
| MWt | 527.54 |
| Formula | C₂₆H₂₈F₃N₇O₂ |