2-Methylthioadenosine diphosphate trisodium

Supplier MedChemExpress
Product # HY-108648-5 mg
CAS # 475193-31-8
Pricing 5 mg, USD $280.0
Biological Activity 2-Methylthioadenosine diphosphate trisodium is a potent purinergic P2Y receptors agonist, with EC50s of 19, 6.2, and 5 nM for human P2Y13, mouse P2Y13 and human P2Y12, respectively. 2-Methylthioadenosine diphosphate trisodium has pEC50s of 8.29 and 5.75 for human P2Y1 and rat P2Y6, respectively. 2-Methylthioadenosine diphosphate trisodium induces platelet aggregation and shape change, and inhibits cyclic AMP accumulation in platelets exposed to prostaglandin E1[1][2][3].
Synonyms 2-Methylthio-ADP trisodium
MWt 539.24
Formula C₁₁H₁₄N₅Na₃O₁₀P₂S
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