Zatebradine
Supplier | MedChemExpress |
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Product # | HY-13422A-50 mg |
CAS # | 85175-67-3 |
Pricing | 50 mg, USD $588.0 |
Synonyms | UL-FS-49 free base; UL-FS-49CL free base |
MWt | 456.57 |
Formula | C₂₆H₃₆N₂O₅ |
Biological Activity | Zatebradine (UL-FS-49 (free base); UL-FS-49CL (free base)) is a potent inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels with an IC50 value of 1.96 µM. Zatebradine blocks the slow inward current through human HCN1, HCN2, HCN3 and HCN4 channels, with IC50 values of 1.83 µM, 2.21 µM, 1.90 µM and 1.88 µM, respectively[1]. |
Purity | 99.0% |