Mothers Against Decapentaplegic Homolog 6 (SMAD6) Antibody
Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1.SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.Binds to regulatory elements in target promoter regions.Tissue specificity: Ubiquitous in various organs, with higher levels in lung.Isoform B is up-regulated in diseased heart tissue.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx015995-100UL |
| Pricing | 100 µl USD $420.5 |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Host | Mouse |
| Tested Applications | ELISA, WB |
| UniProt Primary AC | O43541 |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |