IK1 inhibitor PA-6

Supplier MedChemExpress
Product # HY-112544-5 mg
CAS # 500715-03-7
Pricing 5 mg, USD $80.0
Synonyms PA-6
MWt 492.61
Formula C₃₁H₃₂N₄O₂
Biological Activity IK1 inhibitor PA-6 (PA-6), a pentamidine analogue, is a selective and potent IK1 (KIR2.x ion-channel-carried inward rectifier current) inhibitor, with IC50 values of 12-15 nM for human and mouse KIR2.x currents. IK1 inhibitor PA-6 (PA-6) elevates KIR2.1 protein expression and induces intracellular KIR2.1 accumulation. IK1 inhibitor PA-6 (PA-6) has the potential to treat atrial fibrillation and arrhythmia[1][2][3].
Purity 98.23%
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