Ulixertinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15816-100 mg |
| CAS # | 869886-67-9 |
| Pricing | 100 mg, USD $450.0 |
| Synonyms | BVD-523; VRT752271 |
| MWt | 433.33 |
| Formula | C₂₁H₂₂Cl₂N₄O₂ |
| Biological Activity | Ulixertinib (BVD-523; VRT752271) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib (BVD-523; VRT752271) inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line[1][2]. |
| Purity | 99.92% |