K-Ras ligand-Linker Conjugate 3

Supplier MedChemExpress
Product # HY-130707-1 mg
CAS # 2378261-87-9
Pricing 1 mg, USD $550.0
Biological Activity K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells[1].
MWt 944.15
Formula C₄₉H₆₅N₇O₁₀S
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