JANEX-1
A cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (Janus family kinase 3; IC50 = 78 µM). Has no effect on JAK1, JAK2, or Zap/Syk or Src tyrosine kinases. Acts as a potent inhibitor of glioblastoma cell adhesion and migration. Also reported to block thrombin-induced platelet aggregation.
| Supplier | BOC Sciences |
|---|---|
| Product # | B0084-211627 |
| Pricing | 50 mg/unit USD $199 |
| Cas | 202475-60-3 |
| Molecular Weight | 297.31 |
| Molecular Formula | C16H15N3O3 |
| Canonical SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC |