Doxorubicin hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15142-500 mg |
| CAS # | 25316-40-9 |
| Pricing | 500 mg, USD $264.0 |
| Synonyms | Hydroxydaunorubicin hydrochloride |
| MWt | 579.98 |
| Formula | C₂₇H₃₀ClNO₁₁ |
| Biological Activity | Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy[1][2][3]. |
| Purity | ≥99.0% |