AX-024 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-107390A-10 mM * 1 mL |
| CAS # | 1704801-24-0 |
| Pricing | 10 mM * 1 mL, USD $149.0 |
| Biological Activity | AX-024 hydrochloride is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ~1 nM. AX-024 hydrochloride modulates cell signaling by targeting SH3 domains. AX-024 hydrochloride has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A. |
| Purity | 99.12% |
| MWt | 375.86 |
| Formula | C₂₁H₂₃ClFNO₂ |