Taltobulin
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15584-5 mg |
| CAS # | 228266-40-8 |
| Pricing | 5 mg, USD $160.0 |
| Synonyms | HTI-286; SPA-110 |
| MWt | 473.65 |
| Formula | C₂₇H₄₃N₃O₄ |
| Biological Activity | Taltobulin (HTI-286), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis[1]. |
| Purity | 99.90% |