Microcrystalline Cellulose PH103
Microcrystalline cellulose is a purified, partially depolymerized cellulose that occurs as a white, odorless, tasteless, crystalline powder composed of porous particles. It is commercially available in different particle sizes and moisture grades that have different properties and applications.
| Supplier | CD Formulation |
|---|---|
| Product # | PE0370 |
| Pricing | , Inquire for price |
| product1 | Suspending Agents |
| Molecular Formula | (C6H10O5)n n n≈220 |
| Molecular Weight | ≈36000 |
| Applications | Adsorbent; Suspending agent; Diluent for tablets and capsules; Disintegrating agent for tablets. |
| Safety | This product is widely used in oral pharmaceutical preparations and food, and is a relatively non-toxic and non-irritating substance. This product is not absorbed after oral administration and has almost no potential toxicity. A large amount of use may cause mild diarrhea, and it is not difficult to use as a pharmaceutical excipient. Abuse of certain tablets containing cellulose, such as inhalation or injection administration, can lead to fibrous granulomas. |
| Incompatibilities | This product is incompatible with strong oxidizing agents. |
| Synonyms | Avicel PH 103; Celex PH103; cellulose-gel PH103; Celphere PH103; Ceolus-KG PH103; crystalline-cellulose PH103; E460 PH103; Emcocel PH103; Ethispheres PH103; Fibrocel PH103; Pharmacel PH103; Tabulose PH103; Vivapur PH103 |
| CAS Number | 9004-34-6 |
| Category | Adsorbent; Suspending Agents; Diluent for tablets and capsules; Disintegrant for tablets |
| UNII | OP1R32D61U |
| Chemical Name | Cellulose PH103 |
| Grade | Pharmceutical Excipients |
| Administration route | Oral; Topical |
| Dosage Form | Inhalation; Oral Capsule; Granules; Suspension; Syrup; Tablet; Topical and Vaginal |
| Stability and Storage Conditions | This product is a hygroscopic, but stable substance. Large quantities of storage must be placed in airtight containers in a cool and dry environment. |
| Source and Preparation | Microcrystalline cellulose can be obtained by controlled hydrolysis of α-cellulose with dilute mineral acid solution, and α-cellulose can be obtained from fiber pulp of cellulose-containing plants. After hydrolysis, the hydrolyzed cellulose is filtered and purified, and the water slurry is spray-dried to form dry porous particles with a wide particle size distribution. |