NSC 74859 (S3I-201)

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NSC 74859 (S3I-201) shows potent inhibition of STAT3 DNA-binding activity with IC50 of 86 μM in cell-free assays, and low activity towards STAT1 and STAT5.

Supplier	Selleck Chemicals
Product #	S1155
Sku #	S1155-10mM/1mL
Pricing	10mM/1mL, $78.00

Citations for this product:

A tracheal aspirate-derived airway basal cell model reveals a proinflammatory epithelial defect in congenital diaphragmatic hernia

Richard Wagner, et al., bioRxiv - Developmental Biology 2022

Quote: ... or STAT3 inhibitor S3I-201 (20μM, Cat#S1155, Selleck Chemicals), ALI cultures were treated daily during the first week of differentiation ...

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