| Supplier |
Creative Peptides |
| Product # |
10-101-185 |
| CAS # |
1374248-77-7 |
| Pricing |
Inquire
|
| Synonyms |
MK-1602; MK 1602; MK1602
|
| MolecularFormula |
C29H26F3N5O3
|
| MolecularWeight |
549.5542
|
| Source |
Synthetic
|
| Storage |
-20°C
|
| ShippingCondition |
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
|
| Explanation |
Ubrogepant, also known as MK-1602, is a potent and selective oral calcitonin gene-related peptide (CGRP) receptor antagonist.
|
| Application |
Ubrogepant is investigated for acute treatment of migraines.
|
| Activity |
Antagonist
|
| InChI |
InChI=1S/C29H26F3N5O3/c1-16-20(17-6-3-2-4-7-17)11-22(26(39)37(16)15-29(30,31)32)35-25(38)19-10-18-12-28(13-23(18)34-14-19)21-8-5-9-33-24(21)36-27(28)40/h2-10,14,16,20,22H,11-13,15H2,1H3,(H,35,38)(H,33,36,40)/t16-,20-,22+,28+/m1/s1
|
| InChIKey |
DDOOFTLHJSMHLN-ZQHRPCGSSA-N
|
| Solubility |
Soluble in DMSO, not in water
|
| IsomericSMILES |
C[C@@H]1[C@@H](C[C@@H](C(=O)N1CC(F)(F)F)NC(=O)C2=CC3=C(C[C@@]4(C3)C5=C(NC4=O)N=CC=C5)N=C2)C6=CC=CC=C6
|
| Appearance |
Solid powder
|
| BiologicalActivity |
Ubrogepant (MK-1602) is a novel oral calcitonin gene-related peptide receptor (CGRP) antagonist in development for acute treatment of migraine.
|
| Target |
CGRP Receptor
|
| Purity |
>98% (or refer to the Certificate of Analysis)
|
| ShortTermStorageConditions |
Dry, dark and at 0 - 4 °C
|
| LongTermStorageConditions |
-20 °C
|
| LabelingTarget |
Histone deacetylase
|
| BoilingPoint |
942.8±65.0 °C at 760 mmHg
|