PF-03715455
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-18862 |
| CAS # | 1056164-52-3 |
| Pricing | inquire |
| Biological Activity | PF-03715455 is a potent inhaled p38 MAPK inhibitor. PF-03715455 shows some selectivity for p38α over p38β with respective IC50 values of 0.88 and 23 nM. PF-03715455 potently inhibits LPS-induced TNFα production in human whole blood (IC50=1.7 nM). PF-03715455 has potential for the treatment of COPD (chronic obstructive pulmonary disease)[1][2]. |
| MWt | 700.27 |
| Formula | C₃₅H₃₄ClN₇O₃S₂ |