Mouse Anti-SARS-CoV Recombinant Antibody (clone F26G19); Fab Fragment
F26G19 is a neutralizing mouse monoclonal antibody, elicited by immunization with chemically inactivated SARS-CoV. The RBD-F26G19 Fab complex represents the first example of the structural characterization of an antibody elicited by an immune response to SARS-CoV or any fragment of it. The structure reveals that the RBD surface recognized by F26G19 overlaps significantly with the surface recognized by ACE2 and, as such, suggests that F26G19 likely neutralizes SARS-CoV by blocking the virus-host cell interaction.
| Supplier | Creative Biolabs |
|---|---|
| Product # | HPAB-S0121-YC-F(E) |
| Pricing | Inquiry |
| Host | Mouse |
| Target | SARS-CoV |
| Species Reactivity | SARS-CoV |
| Type | Mouse Fab |
| Applications | Neut |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |