Glesatinib hydrochloride
Supplier | MedChemExpress |
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Product # | HY-19642A-10 mM * 1 mL |
CAS # | 1123838-51-6 |
Pricing | 10 mM * 1 mL, USD $462.0 |
Synonyms | MGCD265 hydrochloride |
MWt | 656.17 |
Formula | C₃₁H₂₈ClF₂N₅O₃S₂ |
Biological Activity | Glesatinib hydrochloride (MGCD265 hydrochloride) is an orally active, potent MET/SMO dual inhibitor. Glesatinib hydrochloride, a tyrosine kinase inhibitor, antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC)[1][2]. |
Purity | ≥98.0% |