Sodium 2-Hydroxypropiomate Solution

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Sodium lactate occurs as a clear, colorless, slightly syrupy liquid. It is odorless, or has a slight odor with a characteristic saline taste. It is hygroscopic.
Supplier CD Formulation
Product # PE0407
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product1 Pharmaceutical Excipients
Molecular Formula C3H5NaO3
Molecular Weight 112.06
Applications Sodium lactate is widely used in cosmetics,food products and pharmaceutical applications including parenteral and topical formulations. Therapeutically, sodium lactate is used in infusions as a component of Ringer-lactate solution; as an alternative for sodium hydrogencarbonate in light acidosis; as a rehydrating agent; and as a carrier for electrolyte concentrates or medicines in perfusion/ infusion solutions.
Safety This product is non-toxic and generally recognized as safe, and ADI has not made restrictive regulations. Patients with severe hepatic impairment who cannot convert lactate to bicarbonate should not use it.
Incompatibilities This product has a compatibility reaction with novobiocin sodium, oxytetracycline hydrochloride, sodium bicarbonate, calcium sodium edetate, sulfadiazine, etc., and it is forbidden to be compatible with it.
Synonyms
  • E325; 2-hydroxypropanoic acid monosodium salt; Lacolin; lactic
  • acid monosodium salt; lactic acid sodium salt; natrii lactatis solutio;
  • Patlac; Purasal; Ritalac NAL; sodium a-hydroxypropionate.
CAS Number 72-17-3
Category Humectants; Stabilizers; pH adjuster; Wetting agents
UNII TU7HW0W0QT
Chemical Name Sodium lactate
Grade Pharmceutical Excipients
Administration route Infiltration; Intraperitoneal; Intravenous; Oral; Intracardiac; Intramuscular; Subcutaneous
Dosage Form
  • Epidural, IM, IV, and SC injections; oral
  • suspensions; topical gels and solutions
Stability and Storage Conditions Sodium lactate should be stored in a well-closed container in a cool,dry, place. Sodium lactate is combustible and decomposes upon heating.
Commonly used amount and the maximum amount The maximum dosage for intravenous injection: 50mg; the maximum dosage for general topical preparations: 51.3mg/g.
Source and Preparation Add sodium hydroxide to lactic acid under cooling conditions to carry out neutralization reaction, then concentrate in vacuum at 50°C to remove 80% of water, and then neutralize with sodium hydroxide, crystallize or not crystallize.
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