Ceritinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15656-1 g |
| CAS # | 1032900-25-6 |
| Pricing | 1 g, USD $750.0 |
| Synonyms | LDK378 |
| MWt | 558.14 |
| Formula | C₂₈H₃₆ClN₅O₃S |
| Biological Activity | Ceritinib (LDK378) is a selective, orally bioavailable, and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib (LDK378) also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib (LDK378) shows great antitumor potency[1][2]. |
| Purity | 99.97% |