Bis-sulfone NHS Ester
Bis-sulfone NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. Please contact us for GMP-grade inquiries.
| Supplier | BOC Sciences |
|---|---|
| Product # | BPG-4397 |
| Pricing | Inquire |
| Cas | 899452-51-8 |
| Molecular Weight | 597.7 |
| Molecular Formula | C29H27NO9S2 |
| Canonical SMILES | CC1=CC=C(C=C1)S(=O)(=O)CC(CS(=O)(=O)C2=CC=C(C=C2)C)C(=O)C3=CC=C(C=C3)C(=O)ON4C(=O)CCC4=O |