ERRα antagonist-1
ERRα antagonist-1, a selective and high affinity antagonist of estrogen-related receptor α (ERRα), inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β with IC50s of 170 and 180 nM, respectively. It does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.
| Supplier | BOC Sciences |
|---|---|
| Product # | 1072145-33-5 |
| Pricing | Inquire |
| Cas | 1072145-33-5 |
| Molecular Weight | 377.53 |
| Molecular Formula | C21H19N3S2 |
| Canonical SMILES | C1CSC(=N1)N2CCSC2=NC3C4=CC=CC=C4C=CC5=CC=CC=C35 |