G-749
G-749 potently inhibits autophosphorylation of FLT3 with IC50 of ≤8 nM. In leukemia cells, G-749 shows antiproliferative activity by inducing apoptosis.
| Supplier | BOC Sciences |
|---|---|
| Product # | 1457983-28-6 |
| Pricing | Inquire |
| Cas | 1457983-28-6 |
| Molecular Weight | 521.41 |
| Molecular Formula | C25H25BrN6O2 |
| Canonical SMILES | CN1CCC(CC1)NC2=NC3=C(C(=O)NC=C3Br)C(=N2)NC4=CC=C(C=C4)OC5=CC=CC=C5 |