Romidepsin
Supplier | MedChemExpress |
---|---|
Product # | HY-15149-5 mg |
CAS # | 128517-07-7 |
Pricing | 5 mg, USD $300.0 |
Synonyms | FK 228; FR 901228; NSC 630176 |
MWt | 540.7 |
Formula | C₂₄H₃₆N₄O₆S₂ |
Biological Activity | Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively[1]. Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis[2]. |
Purity | 99.98% |