PF-CBP1 hydrochloride

Supplier MedChemExpress
Product # HY-19999A-25 mg
CAS # 2070014-93-4
Pricing 25 mg, USD $150.0
Biological Activity PF-CBP1 hydrochloride is a highly selective inhibitor of the CREB binding protein bromodomain (CBP BRD). PF-CBP1 inhibits CREBBP and EP300 bromodomains with IC50 of 125 nM and 363 nM respectively. PF-CBP1 hydrochloride reduces LPS-induced inflammatory cytokines expression (IL-1β, IL-6 and IFN-β) in primary macrophages. PF-CBP1 hydrochloride also downregulates RGS4 expression cortical neurons and can be used for the research of neurological disorders, including epilepsy and parkinson's disease, et al[1].
Purity 99.85%
MWt 525.08
Formula C₂₉H₃₇ClN₄O₃
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