RO2959 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-113618A-5 mg |
| CAS # | 1219927-22-6 |
| Pricing | 5 mg, USD $350.0 |
| Biological Activity | RO2959 hydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 hydrochloride is a potent blocker of store operated calcium entry (SOCE) mediated by Orai1/Stim1 channels with an IC50 of 25 nM. RO2959 hydrochloride is also a potent inhibitor of human IL-2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways[1][2]. |
| Formula | C₂₁H₁₉F₂N₅OS.xHCl |