DB1976 dihydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-135797A-10 mg |
| CAS # | 2369663-93-2 |
| Pricing | 10 mg, USD $750.0 |
| Biological Activity | DB1976 dihydrochloride is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 dihydrochloride potently inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, KD of 12 nM) in vitro. DB1976 dihydrochloride has apoptosis-inducing effect[1][2][3]. |
| Purity | ≥98.0% |
| MWt | 520.28 |
| Formula | C₂₀H₁₈Cl₂N₈Se |