Dasatinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10181-10 mM * 1 mL |
| CAS # | 302962-49-8 |
| Pricing | 10 mM * 1 mL, USD $73.0 |
| Synonyms | BMS-354825 |
| MWt | 488.01 |
| Formula | C₂₂H₂₆ClN₇O₂S |
| Biological Activity | Dasatinib (BMS-354825) is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib inhibits Bcr-Abl and Src with IC50s of <1.0 nM and 0.5 nM, respectively[1]. Dasatinib also induces apoptosis and autophagy. |
| Purity | 99.85% |