Supplier |
Creative Peptides |
Product # |
10-101-85 |
CAS # |
107444-51-9 (net) |
Pricing |
Inquire
|
Synonyms |
Glucagon-Like Peptide 1 (7-36) amide; GLP1; GLP-1; Proglucagon; Glucagon-Like-Peptide
|
MolecularFormula |
C149H226N40O45
|
MolecularWeight |
3297.68
|
Source |
Synthetic
|
Sequence |
H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2 acetate salt
|
Explanation |
Glucagon-like peptide-1 (GLP-1) is an incretin derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a gut hormone. Its physiological functions include promoting insulin sensitivity, decreasing food intake by increasing satiety in brain and increasing insulin secretion from the pancreas in a glucose-dependent manner.
|
Application |
GLP-1 (7-36) amide Acetate augments glucose-induced insulin secretion and simultaneously inhibits glucagon secretion and gastric emptying.
|
AreasOfInterest |
Diabetes
|
LongTermStorageConditions |
−20°C
|