Synucleozid hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-135902A-5 mg |
| Pricing | 5 mg, USD $350.0 |
| Synonyms | NSC 377363 hydrochloride |
| MWt | 404.9 |
| Formula | C₂₂H₂₁ClN₆ |
| Biological Activity | Synucleozid hydrochloride (NSC 377363 hydrochloride) is a potent inhibitor of the SNCA mRNA that encodes α-synuclein protein (IC50=1.5 μM). Synucleozid selectively targets the α-synuclein mRNA 5′ UTR at the designed IRE site, decreases the amount of SNCA mRNA loaded into polysomes and thereby inhibits SNCA translation. Synucleozid has the potential for the investigation of Parkinson’s disease[1]. |
| Purity | 98.33% |