| Supplier |
Creative Peptides |
| Product # |
X21176 |
| Pricing |
Inquire
|
| MolecularWeight |
1675.9
|
| Sequence |
- One Letter Code: Mca-RPKPVE-Nva-WR-K(Dnp)-NH2
- Three Letter Code: Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2
|
| Storage |
-20°C
|
| Explanation |
NFF-3 is hydrolyzed rapidly by MMP-3 (kcat/Km = 218,000 s-1 M-1) and very slowly by MMP-9 (kcat/Km = 10,100 s-1 M-1), but no significant hydrolysis by MMP-1 and MMP-2. It is one of the few synthetic substrates selectively hydrolyzed by certain members of the MMP family and thus has important applications for the differentiation of MMP-3 activity from that of other MMPs. Abs/Em = 325/393 nm.
|
| Reference |
- 1. Bremer, C. et al. Acad. Radiol. 9 Suppl 2, S314 (2002);
- 2. Nagase, H. et al. J. Biol. Chem. 269, 20952 (1994).
|