Human 26S Proteasome Non-ATPase Regulatory Subunit 7 (PSMD7) Protein
Recombinant Proteasome 26S Subunit, Non ATPase 7 (PSMD7) is a recombinant Human protein produced in E. coli using Prokaryotic expression. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.
Supplier | Abbexa Ltd. |
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Product # | abx068724-50UG |
Pricing | 50 µg USD $464.0 |
Conjugation | Unconjugated |
Host | E. coli |
Tested Applications | WB, SDS-PAGE |
UniProt Primary AC | P51665 |
Activity | Not tested |
Dry Ice | No |
Availability | Shipped within 5-7 working days. |
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